abstract：:The presence of myocardial interstitial edema in acute myocarditis (AM) leads to thickening of the ventricular wall, and conduction disturbances, such as complete atrioventricular block (CAV), also frequently develop. This study was undertaken in order to clarify the relationship between conduction disturbances and my...

journal_title：Heart and vessels

authors： Morimoto S,Kato S,Hiramitsu S,Uemura A,Ohtsuki M,Kato Y,Sugiura A,Miyagishima K,Yoshida Y,Hishida H

更新日期：2006-11-01 00:00:00

abstract：:Vascular smooth muscle cell (VSMC) differentiation and phenotypic modulation are characterized by changes in gene expression for smooth muscle (SM) marker contractile proteins such as SM alpha-actin and SM22alpha. Hyperplasia suppressor gene (HSG) is a potent VSMC proliferation-inhibiting factor; however, it is not kn...

journal_title：Heart and vessels

authors： Jiang GJ,Han M,Zheng B,Wen JK

更新日期：2006-09-01 00:00:00

abstract：:T cells are involved in the pathogenesis of atherosclerosis. We aimed to search for any association between the peripheral T-cell activities and atherogenic risk factors in healthy subjects. Fifty male volunteers (age 22.0 +/- 2.4 years) were enrolled. No subject had any chronic disease or was under any drug treatment...

journal_title：Heart and vessels

authors： Sonmez A,Kisa U,Uckaya G,Eyileten T,Kinalp C,Yilmaz MI,Dogru T,Turan M,Kocar IH

更新日期：2006-07-01 00:00:00

abstract：:The coronary flow velocity reserve (CFR) is decreased in patients with aortic valve stenosis (AS). The aim of the present prospective study was to examine the CFR in AS patients with normal epicardial coronary arteries during a 3-year follow-up of aortic valve replacement (AVR). A total of 30 AS patients (17 women and...

journal_title：Heart and vessels

authors： Nemes A,Forster T,Kovács Z,Csanády M

更新日期：2006-05-01 00:00:00

abstract：:Angiotensin II type 2 receptor (AT2R) has been proved to be involved in a cardioprotective role, but only a few studies have addressed the association of AT2R-genotype with this role. Whether the AT2R genotype is associated with hypertension is controversial. The aim of the study was to explore the information of sing...

journal_title：Heart and vessels

authors： Zhang M,Ma H,Wang BS,Zhao YZ

更新日期：2006-03-01 00:00:00

abstract：:Primary cardiac osteosarcomas are uncommon tumors. Their growth pattern is aggressive and the prognosis is poor. A 34-year-old, 7-month pregnant woman with a primary cardiac osteosarcoma associated with the anterior mitral leaflet and connected to the interatrial septum, causing nearly subtotal obstruction of the mitr...

journal_title：Heart and vessels

authors： Koçak H,Karapolat S,Gündogdu C,Bozkurt E,Unlü Y

更新日期：2006-01-01 00:00:00

abstract：:Taurine (2-aminoethanesulfonic acid) is a potent antioxidant and inhibits cell apoptosis in ischemic reperfusion injury. In this study we evaluated whether addition of taurine to St. Thomas' cardioplegic solution enhances its myocardial protective effects in prolonged hypothermic heart preservation in rats. Hearts iso...

journal_title：Heart and vessels

authors： Oriyanhan W,Yamazaki K,Miwa S,Takaba K,Ikeda T,Komeda M

更新日期：2005-11-01 00:00:00

abstract：:Coronary blood flow was quantified using the thrombosis in myocardial infarction (TIMI) frame-count method. This measurement has been significantly correlated with flow velocity measured invasively by use of a Doppler flow wire. Coronary artery ectasia or aneurysm (CEA) is thought to be present in patients with a slow...

journal_title：Heart and vessels

authors： Kosar F,Acikgoz N,Sahin I,Topal E,Aksoy Y,Cehreli S

更新日期：2005-09-01 00:00:00

abstract：:Treatment with inhibitors of 3-hydroxyl-3-methylglutaryl coenzyme A reductase (statins) reduces the incidence of cardiovascular events, but it is unclear whether the beneficial effects are mediated solely by their lipid-lowering properties. We therefore investigated whether atorvastatin reduces inflammation and oxidat...

journal_title：Heart and vessels

authors： Sugiyama M,Ohashi M,Takase H,Sato K,Ueda R,Dohi Y

更新日期：2005-07-01 00:00:00

abstract：:Based on the unique property of fluorine-18 fluorodeoxyglucose, localization and follow-up of hypermetabolic processes is possible with positron emission tomography (PET). The dual-modality PET/computed tomography (CT) systems provide intrinsically fused morphologic and functional data in a single examination. We repo...

journal_title：Heart and vessels

authors： Kröger K,Antoch G,Goyen M,Freudenberg LS,Veit P,Janicke I,Bockisch A,Forsting M

更新日期：2005-07-01 00:00:00

abstract：:A transient left ventricular apical ballooning (so-called "ampulla" or "Takotsubo-shaped" cardiomyopathy) with type I CD36 deficiency is described in a 71-year-old woman. The patient was referred because of chest pain and worsening of dyspnea. Electrocardiogram showed T-wave inversions on the precordal leads, and acut...

journal_title：Heart and vessels

authors： Kushiro T,Saito F,Kusama J,Takahashi H,Imazeki T,Tani S,Kikuchi S,Imai S,Matsudaira K,Watanabe I,Hino T,Sato Y,Nakayama T,Nagao K,Kanmatsuse K

更新日期：2005-05-01 00:00:00

abstract：:Left ventricular (LV) dilatation following myocardial infarction (MI) is a major determinant of the patient's prognosis, and myocardial energy metabolism may play a key role in LV remodeling. We aimed to investigate the relative timing of LV dilatation to LV function, myocardial energy regulation by uncoupling protein...

journal_title：Heart and vessels

authors： Guo P,Mizushige K,Noma T,Murakami K,Namba T,Ishizawa M,Tsuji T,Kimura S,Kohno M

更新日期：2005-03-01 00:00:00

abstract：:Anatomic continuity between the anterior mitral leaflet and the aortic root may predispose those patients with aortic root pathology to functional changes of the mitral valve without any involvement of this valve. A 34-year-old man presented with aortic valve endocarditis. Transthoracic echocardiograpy showed severe a...

journal_title：Heart and vessels

authors： Gunay I,Mert M,Kucukoglu S,Ozkan AA,Okcun B

更新日期：2005-02-01 00:00:00

abstract：:The role of inflammation in acute coronary syndrome (ACS) and the mechanism by which statin treats ACS is explored. Serum high-sensitivity C-reactive protein (hs-CRP) and interleukin-6 (IL-6) levels were measured in 50 patients with ACS [including 30 cases with unstable angina (UA) and 20 patients with acute myocardia...

journal_title：Heart and vessels

authors： Luo Y,Jiang D,Wen D,Yang J,Li L

更新日期：2004-11-01 00:00:00

abstract：:It has been shown that green tea catechins (GTC) suppress proliferation of vascular smooth muscle cells (VSMCs) and that epigallocatechin-3-gallate (EGCG), which is a major constituent of GTC, selectively inhibits the platelet-derived growth factor-BB (PDGF-BB)-induced intracellular signaling transduction pathway. Vas...

journal_title：Heart and vessels

authors： Kim DW,Park YS,Kim YG,Piao H,Kwon JS,Hwang KK,Youn TJ,Park JB,Yun YP,Sachinidis A,Kim CH,Cho MC,Ahn HY

更新日期：2004-09-01 00:00:00

abstract：:Ischemic cardiomyopathy complicated by severe mitral regurgitation (MR) has a poor prognosis. In such cases, whether mitral valve repair for MR improves the prognosis of survival remains unclear. In this study, 50 patients diagnosed with ischemic cardiomyopathy at our hospital between August 1991 and August 1996 were ...

journal_title：Heart and vessels

authors： Uchikawa S,Ohtaki E,Sumiyoshi T,Hosoda S,Kasegawa H

更新日期：2004-07-01 00:00:00

abstract：:Vascular calcification is an ectopic calcification that commonly occurs in atherosclerosis. Because taurine was previously shown to protect against cardiovascular diseases, the effect of taurine on vascular calcification was evaluated in calcified vascular smooth muscle cells (VSMCs) of rat in vitro in the present stu...

journal_title：Heart and vessels

authors： Li J,Zhang B,Huang Z,Wang S,Tang C,Du J

更新日期：2004-05-01 00:00:00

abstract：:Cardiac systolic (left ventricular ejection fraction) and diastolic (mitral inflow velocity pattern and/or mitral deceleration time) function were reported as predictors of clinical outcome or left ventricular remodeling in patients with acute myocardial infarction (AMI). Recently, a new index (Doppler-derived index c...

journal_title：Heart and vessels

authors： Sasao H,Noda R,Hasegawa T,Endo A,Oimatsu H,Takada T

更新日期：2004-03-01 00:00:00

abstract：:Wave intensity analysis is a method of studying intravascular flow wave propagation, calculated as the product of the rate of change in pressure (d P/ t) and the rate of change in velocity (d U/d t). The typical pattern of wave intensity seen during the cardiac cycle has two dominant peaks. The larger first peak (FP) ...

journal_title：Heart and vessels

authors： Fujimoto S,Mizuno R,Saito Y,Nakamura S

更新日期：2004-01-01 00:00:00

abstract：:We studied the effects of cobalt-60 Gamma-radiation on the gene expression and secretion of adrenomedullin (Adm) and endothelin (ET) in cultured rat vascular smooth muscle cells (VSMCs). Rat VSMCs cultured in Dulbecoo's modified Eagle's medium containing 10% FBS were radiated with cobalt-60 Gamma-radiation at doses of...

journal_title：Heart and vessels

authors： Zhong G,Chen F,Bu D,Li J,Qi Y,Niu D,Wang S,Pang Y,Tang C

更新日期：2003-09-01 00:00:00

abstract：:This study was designed to test the ability of adenovirus-delivered vascular endothelial growth factor (Ad-VEGF) to stimulate angiogenesis and arteriogenesis in the rabbit hindlimb following the induction of ischemia and to evaluate the functional changes in the collateral circulation. Ten days after the surgical indu...

journal_title：Heart and vessels

authors： Hershey JC,Baskin EP,Corcoran HA,Bett A,Dougherty NM,Gilberto DB,Mao X,Thomas KA,Cook JJ

更新日期：2003-07-01 00:00:00

abstract：:Although heparin allergy is a rare but well-documented entity, anticoagulation management for cardiac surgery in patients with the heparin allergy has not been established due to its rarity. Here we report a case that shows our anticoagulation strategy during a coronary bypass operation. A 67-year-old man with unstabl...

journal_title：Heart and vessels

authors： Ohno H,Higashidate M,Yokosuka T

更新日期：2003-03-01 00:00:00

abstract：:We present a case of a 38-year-old woman with intravenous leiomyomatosis originating from the uterus involving the right ventricle, right atrium, inferior vena cava, and iliac veins. Tumors in the heart and the inferior vena cava were removed using cardiopulmonary bypass and circulatory arrest; 10 days after the cardi...

journal_title：Heart and vessels

authors： Gaudino M,Spatuzza P,Snider F,Luciani N,Cina G,Possati G

更新日期：2002-12-01 00:00:00

abstract：:This study aimed to search genes altered in expression after long-term treatment with the angiotensin II type 1 receptor (AT1) antagonist, CV-11974, in volume-overloaded hearts. Arteriovenous shunt was made between the common carotid artery and jugular vein in Japanese White rabbits. Shunt-operated rabbits were random...

journal_title：Heart and vessels

authors： Itoh M,Takeishi Y,Nakada S,Miyamoto T,Tsunoda Y,Takahashi H,Kubota I,Tomoike H

更新日期：2002-11-01 00:00:00

abstract：:The aim of our study was to assess the atherosclerotic burden in patients with the first symptoms of coronary artery disease (CAD). The study population consisted of 100 consecutive patients (new-onset severe angina or myocardial infarction) and 70 age- and sex-matched volunteers without symptoms of CAD. Functional an...

journal_title：Heart and vessels

authors： Cerne A,Kranjec I

更新日期：2002-09-01 00:00:00

abstract：:It is known that the heart of an athlete has been physiologically adapted by prolonged training. There are a large number of echocardiographic studies which have focused on left ventricular wall thickness and dilatation, but there are few studies concerning right heart function in the athlete's heart. The aim of this ...

journal_title：Heart and vessels

authors： Erol MK,Karakelleoglu S

更新日期：2002-07-01 00:00:00

abstract：:In a mass chest computed tomography (CT) screening using a mobile helical CT unit, we measured the aortic diameter at three segments to confirm standard values and also attempted to detect any asymptomatic aortic aneurysms. The population screened in the present study consisted of 6971 subjects (3847 men and 3124 wome...

journal_title：Heart and vessels

authors： Itani Y,Watanabe S,Masuda Y,Hanamura K,Asakura K,Sone S,Sunami Y,Miyamoto T

更新日期：2002-01-01 00:00:00

abstract：:The subendocardial side of myocardium makes a major contribution to left ventricular (LV) contraction and is very susceptible to ischemia. In this study we sought to quantify regional wall motion during low-dose dobutamine stress echocardiography (DSE) by using the myocardial velocity gradient (MVG) derived from tissu...

journal_title：Heart and vessels

authors： Tsutsui H,Uematsu M,Yamagishi M,Haruta S,Shimakura T,Miyatake K

更新日期：2000-01-01 00:00:00

abstract：:In the present study, we investigated whether gallic acid (GA) can induce death in cultured vascular smooth muscle cells (VSMCs), and whether production of the hydroxyl radical (.OH) is involved in the process of GA action. GA killed cultured VSMCs from rat aorta, in a dosc- and time-dependent manner. Cytoplasmic shri...

journal_title：Heart and vessels

authors： Qiu X,Takemura G,Koshiji M,Hayakawa Y,Kanoh M,Maruyama R,Ohno Y,Minatoguchi S,Akao S,Fukuda K,Fujiwara T,Fujiwara H

更新日期：2000-01-01 00:00:00

abstract：:The thrombotest (TT) technique has been widely used in Japan for monitoring oral anticoagulant therapy (OAT). The therapeutic range was originally recommended to be 10%-25%. However, the International Committee for Standardization in Hematology/International Committee on Thrombosis and Hemostasis (ICSH/ICTH) recommend...

journal_title：Heart and vessels

authors： Uetsuka Y,Hosoda S,Kasanuki H,Aosaki M,Murasaki K,Ooki K,Inoue M,Akiyama E,Kitada M

更新日期：2000-01-01 00:00:00

abstract：:The modulation of L-type Ca2+ currents (I(Ca,L)) by the basal activities of G proteins was studied in adult guinea pig ventricular myocytes by whole-cell patch-clamp techniques. With intrapipette guanosine triphosphate (GTP) (100 microM), a specific inhibition of G1 proteins by pertussis toxin (PTX) produced an increa...

journal_title：Heart and vessels

authors： Makita T,Horie M,Xie LH,Okada Y,Sasayama S

更新日期：2000-01-01 00:00:00

abstract：:Although the ultimate cause for the myocardial dysfunction of hypertensive heart disease is still unclear, a crucial role of the myocardial energy metabolism has been suggested. Therefore, the aim of the present study was to investigate whether age-related myocardial dysfunction in hearts of spontaneously hypertensive...

journal_title：Heart and vessels

authors： Perings SM,Schulze K,Decking U,Kelm M,Strauer BE

更新日期：2000-01-01 00:00:00

abstract：:The records of 153 patients with doubly committed subarterial ventricular septal defect (DCVSD) who underwent intracardiac repair were analyzed to evaluate factors responsible for aortic valve leaflet deformity. The patients were divided into two groups according to their echocardiographic and angiographic features as...

journal_title：Heart and vessels

authors： Kobayashi J,Koike K,Senzaki H,Kobayashi T,Tsunemoto M,Ishizawa A,Ohta Y,Shimada M,Omoto R

更新日期：1999-01-01 00:00:00

abstract：:Wave intensity (WI) is a new hemodynamic index, which is defined as (dP/dt)(dU/dt) at any site of the circulation, where dP/dt and dU/dt are the time derivatives of blood pressure and velocity, respectively. Arterial WI in normal subjects has two positive sharp peaks. The first peak occurs during early systole when a ...

journal_title：Heart and vessels

authors： Niki K,Sugawara M,Uchida K,Tanaka R,Tanimoto K,Imamura H,Sakomura Y,Ishizuka N,Koyanagi H,Kasanuki H

更新日期：1999-01-01 00:00:00

abstract：:Scanning electron microscopy was used to compare the shape, size, and connection of left ventricular (LV) myocytes between spontaneously hypertensive rats (SHR) and Wistar Kyoto rats (WKY) at 3, 8, 15, 35, and 63 weeks of age. For either strain at each age, five rats were studied, in which LV myocytes consisted of a c...

journal_title：Heart and vessels

authors： Okabe M,Kawamura K,Terasaki F,Hayashi T

更新日期：1999-01-01 00:00:00

abstract：:The purpose of this study was to examine the histopathological findings of right ventricular endomyocardial biopsies from ten patients less than 60 years of age (47 +/- 9.8 (mean +/- SD) years) with documented atrioventricular block but without apparent heart disease. They underwent electrophysiological testing, echoc...

journal_title：Heart and vessels

authors： Teragaki M,Toda I,Sakamoto K,Shimada K,Yamagishi H,Yoshiyama M,Akioka K,Kawase Y,Nishimoto M,Takeuchi K,Yoshikawa J

更新日期：1999-01-01 00:00:00

abstract：:Myocardial ischemia leads to the activation of neutrophils as well as endothelial cells. The interaction between these cells is dependent on certain adhesion glycoproteins which are expressed on their surface. Adhesion of neutrophils to endothelium, mediated by adhesion molecules, has been shown to result in coronary ...

journal_title：Heart and vessels

authors： Siminiak T,Smielecki J,Dye JF,Baliñski M,El-Gendi H,Wysocki H,Sheridan DJ

更新日期：1998-01-01 00:00:00

abstract：:Hydrogen peroxide (H2O2) elicited concentration-dependent relaxation of endothelium-denuded rings of porcine coronary arteries. The relaxation induced by the H2O2 was markedly attenuated by 10 microM 1H-[1,2,4]oxadiazolo [4,3,a]quinoxalin-1-one (ODQ), an inhibitor of soluble guanylate cyclase, or by 100 nM charybdotox...

journal_title：Heart and vessels

authors： Hayabuchi Y,Nakaya Y,Matsuoka S,Kuroda Y

更新日期：1998-01-01 00:00:00

abstract：:There are few studies regarding the assessment of left ventricular contractile function in patients with atrial fibrillation (AF). The aim of this study was to assess the left ventricular (LV) contractile function, i.e., the end-systolic pressure-volume relation (Ees) and a recently developed LV systolic myocardial st...

journal_title：Heart and vessels

authors： Tanaka R,Tomita M,Noda T,Kagawa K,Nishigaki K,Yamaguchi M,Kunishima A,Fujiwara H

更新日期：1998-01-01 00:00:00

abstract：:Previous studies assessing vascular responses in nonexercising beds during exercise in patients with chronic heart failure (CHF) have yielded varying results. We proposed that the clinical and hemodynamic severity of heart failure may explain some of the variation. We reasoned that diastolic ventricular interaction (D...

journal_title：Heart and vessels

authors： Atherton JJ,Dryburgh LG,Thomson HL,Moore TD,Wright KN,Muehle GW,Fitzpatrick LE,Frenneaux MP

更新日期：1998-01-01 00:00:00